Phenescaline

Phenescaline

Phenescaline is a psychedelic drug and phenethylamine derivative which is related to mescaline. It was first synthesized by Alexander Shulgin.

History

Phenescaline was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage as 120-160 mg and the duration as 10–15 hours. He reports that phenescaline produces an array of psychedelic effects similar to those of mescaline, but with a less intense visual hallucination component.

Chemistry

Phenescaline, or 3,5-dimethoxy-4-phenethylphenethylamine, is a phenethylamine with the formula C16H21NO2. It is a member of the 2C family of psychedelic phenethylamines, all of which are derivatives of mescaline.

Pharmacology

Like other psychedelic phenethylamines, phenescaline likely acts as a 5-HT2A receptor agonist. The 5-HT2A receptor is responsible for many of the psychedelic effects produced by phenethylamines and other psychedelic drugs.

Effects

Phenescaline produces a range of psychedelic effects, including altered states of consciousness, visual hallucinations, and synesthesia. The effects are reported to be less intense than those of mescaline, but longer lasting.

Legal status

Phenescaline is not controlled at the federal level in the United States, but it could be considered an analog of a Schedule I drug under the Federal Analogue Act.

See also

• Mescaline
• 2C family
• Psychedelic drug
• Alexander Shulgin
• PiHKAL

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