Polysorbate 80

From WikiMD's medical encyclopedia

Polysorbate 80 Food additive E433

Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. It is a derivative of sorbitan esterified with fatty acids, primarily oleic acid. Polysorbate 80 is known for its ability to stabilize oil-in-water mixtures, making it a valuable ingredient in various formulations.

Chemical Structure and Properties

Polysorbate 80, also known as Tween 80, has the chemical formula C64H124O26. It is a viscous, water-soluble yellow liquid. The hydrophilic groups in Polysorbate 80 are polyoxyethylene chains, which are responsible for its solubility in water, while the hydrophobic groups are derived from oleic acid.

Uses

Food Industry

In the food industry, Polysorbate 80 is used as an emulsifier to improve the texture and consistency of products. It is commonly found in ice cream, salad dressings, and baked goods. Its ability to prevent the separation of ingredients makes it a popular additive.

Cosmetics and Personal Care

Polysorbate 80 is widely used in cosmetics and personal care products such as lotions, creams, and shampoos. It helps to mix oil and water-based ingredients, ensuring a uniform product.

Pharmaceuticals

In the pharmaceutical industry, Polysorbate 80 is used as an excipient in the formulation of various medications. It helps to solubilize active ingredients and improve the bioavailability of drugs.

Safety and Regulations

Polysorbate 80 is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA) when used in accordance with good manufacturing practices. However, some individuals may experience allergic reactions or sensitivities to this compound.

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Contributors: Prab R. Tumpati, MD