Primary cutaneous follicle center lymphoma

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Primary cutaneous follicle center lymphoma

Primary cutaneous follicle center lymphoma (PCFCL) is a type of non-Hodgkin lymphoma that originates in the skin. It is a rare condition, accounting for approximately 60% of all primary cutaneous B-cell lymphomas.

Pronunciation

Primary cutaneous follicle center lymphoma is pronounced as "pry-mary kyu-tay-nee-us fuh-li-kuhl sen-ter lim-foh-muh".

Etymology

The term "Primary cutaneous follicle center lymphoma" is derived from its characteristics. "Primary" indicates that the lymphoma originates in the skin, "cutaneous" refers to the skin, "follicle center" refers to the part of a lymph node where B cells mature, and "lymphoma" is a type of cancer that begins in the cells of the lymphatic system.

Related Terms

  • Non-Hodgkin lymphoma: A group of blood cancers that includes all types of lymphoma except Hodgkin's lymphomas.
  • B-cell lymphoma: A type of non-Hodgkin lymphoma that affects B cells.
  • Lymph node: A small, bean-shaped organ of the immune system, distributed widely throughout the body including the armpit and stomach and linked by lymphatic vessels.
  • Lymphatic system: The network of tissues and organs that help rid the body of toxins, waste and other unwanted materials.

Symptoms

Symptoms of PCFCL can vary but often include:

  • Reddish or purple skin lesions that do not itch and are most commonly found on the scalp, forehead, or trunk.
  • The lesions may be solitary or grouped.
  • They are slow-growing and can be present for months to years before diagnosis.

Diagnosis

Diagnosis of PCFCL often involves a skin biopsy, where a small sample of the skin lesion is removed and examined under a microscope. Further tests may be required to determine if the lymphoma has spread to other parts of the body.

Treatment

Treatment options for PCFCL can include radiation therapy, surgical excision, and in some cases, chemotherapy or immunotherapy.

External links

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