Pyroglutamyl-peptidase I
Pyroglutamyl-peptidase I
Pyroglutamyl-peptidase I (pronunciation: py-ro-glu-tam-yl pep-ti-dase one), also known as PGP I or PGP1, is an enzyme that in humans is encoded by the PGP1 gene.
Etymology
The term Pyroglutamyl-peptidase I is derived from the Greek words 'pyro' meaning fire, 'glutamyl' referring to the amino acid glutamic acid, and 'peptidase' indicating that it is a type of enzyme that breaks down peptides. The 'I' denotes that it is the first enzyme of this type to be discovered.
Function
Pyroglutamyl-peptidase I is an enzyme that catalyzes the removal of pyroglutamic acid (also known as pyroglutamate) from the N-terminal of peptides and proteins. This enzyme plays a crucial role in the metabolism of neuropeptides and hormones.
Related Terms
- Enzyme: A protein that acts as a biological catalyst.
- Gene: The basic physical and functional unit of heredity.
- Amino Acid: Organic compounds that combine to form proteins.
- Peptide: Short chains of amino acid monomers linked by peptide (amide) bonds.
- Pyroglutamic Acid: A derivative of the amino acid glutamic acid.
- Neuropeptide: Small protein-like molecules used by neurons to communicate with each other.
- Hormone: Chemical messengers that are secreted directly into the blood, which carries them to organs and tissues of the body to exert their functions.
External links
- Medical encyclopedia article on Pyroglutamyl-peptidase I
- Wikipedia's article - Pyroglutamyl-peptidase I
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