Ro48-8684

Ro48-8684

Ro48-8684 (pronunciation: /roʊ 48 8684/) is a benzodiazepine derivative drug, which is a minor tranquilizer. It was developed by Hoffmann-La Roche in the 1990s.

Etymology

The name "Ro48-8684" is derived from the company that developed it, Hoffmann-La Roche, and the specific number assigned to the compound during its development.

Pharmacology

Ro48-8684 is a partial agonist at GABA_A receptors. This means it binds to these receptors but only partially activates them, resulting in less intense effects compared to full agonists. It has a high affinity for the α2 and α3 subtypes of GABA_A receptors.

Medical Uses

Ro48-8684 has been investigated for use in the treatment of anxiety, insomnia, and seizures. However, it has not been widely adopted in clinical practice due to its relatively low potency and efficacy compared to other benzodiazepines.

Related Terms

• Benzodiazepine
• [[GABA_A receptor]]
• Partial agonist
• Anxiety
• Insomnia
• Seizures

[[Category:GABA_A receptor agonists]]

External links

• Medical encyclopedia article on Ro48-8684
• Wikipedia's article - Ro48-8684

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