Rotenone
Rotenone
Rotenone (/roʊˈtɛnoʊn/ roh-TEN-ohn) is a naturally occurring compound derived from the roots and stems of several plants, particularly those belonging to the family Leguminosae (Fabaceae). It is used as a broad-spectrum insecticide, piscicide, and pesticide.
Etymology
The term "rotenone" is derived from the plant R. elliptica, commonly known as "roteno" or "cube," from which the compound was first isolated.
Usage
Rotenone is primarily used in gardening and agriculture as a non-specific insecticide and pesticide. It is also used in fisheries as a piscicide to manage and eradicate invasive fish species.
Mechanism of Action
Rotenone works by inhibiting the transfer of electrons from Complex I to ubiquinone in the electron transport chain, thereby disrupting cellular respiration in insects and fish.
Health Effects
Exposure to rotenone can cause a range of health effects in humans, including skin and eye irritation, nausea, vomiting, and in severe cases, respiratory failure. Some studies have suggested a link between rotenone exposure and Parkinson's disease, although this connection is not fully understood.
Related Terms
External links
- Medical encyclopedia article on Rotenone
- Wikipedia's article - Rotenone
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