Schistosoma japonicum
Schistosoma japonicum is a species of parasitic flatworms known as blood flukes. They belong to the genus Schistosoma, which is responsible for the disease schistosomiasis. Schistosoma japonicum is found predominantly in Asia, particularly in China, the Philippines, and parts of Indonesia.
Life Cycle
The life cycle of Schistosoma japonicum involves two hosts: a definitive host (humans and other mammals) and an intermediate host (snails of the genus Oncomelania). The adult worms live in the blood vessels of the host, where they produce eggs. Some of these eggs are passed out of the host's body in the feces, while others are trapped in the host's tissues, causing an immune response and subsequent damage.
Transmission
Transmission of Schistosoma japonicum occurs when the eggs in the feces come into contact with water, where they hatch into miracidia. These miracidia infect the snail intermediate host, where they develop into sporocysts, then into cercariae. The cercariae are released from the snail into the water, where they can penetrate the skin of a human or other mammal host, completing the life cycle.
Symptoms and Treatment
Infection with Schistosoma japonicum can cause a range of symptoms, from mild to severe. These can include abdominal pain, diarrhea, and blood in the stool or urine. In severe cases, the disease can cause liver and spleen enlargement, ascites, and even death. Treatment typically involves the use of the drug praziquantel, which kills the adult worms.
Prevention
Prevention of schistosomiasis caused by Schistosoma japonicum involves a combination of strategies, including snail control, provision of safe water and sanitation, health education, and periodic drug treatment of at-risk populations.
See Also
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Contributors: Prab R. Tumpati, MD