Serum creatinine
Serum Creatinine
Serum creatinine (pronounced: /ˈsɪərəm kriːˈætɪniːn/) is a blood measurement that is widely used as an indicator of kidney function.
Etymology
The term "creatinine" comes from the Greek word "kreas," which means flesh. The "ine" suffix was added because it was first isolated from meat or flesh. The prefix "serum" refers to the clear liquid that separates from the blood when it clots.
Definition
Serum creatinine is a waste product that is produced continuously during normal muscle breakdown. The kidneys filter creatinine from the blood into the urine, and the creatinine level in the blood remains relatively constant. The creatinine level in the blood is a useful measure of the glomerular filtration rate (GFR), the rate at which the kidneys filter waste from the blood.
Related Terms
- Glomerular Filtration Rate (GFR): The rate at which the kidneys filter waste from the blood.
- Renal function: The state of the kidneys and how well they filter waste from the blood.
- Kidney disease: A condition in which the kidneys are damaged and cannot filter blood as well as healthy kidneys.
- Chronic Kidney Disease (CKD): Long-standing, progressive deterioration of renal function.
- Acute Kidney Injury (AKI): An abrupt loss of kidney function that develops within 7 days.
Measurement
Serum creatinine is usually measured in milligrams (mg) per deciliter (dL) of blood. The normal range for creatinine in the blood may be 0.84 to 1.21 milligrams per deciliter, although this can vary from lab to lab, between men and women, and by age.
Interpretation
High levels of serum creatinine can indicate kidney damage or chronic kidney disease. Low levels can be seen in conditions such as muscle wasting or malnutrition.
External links
- Medical encyclopedia article on Serum creatinine
- Wikipedia's article - Serum creatinine
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