Substantia innominata

Substantia Innominata is a region of the brain that is part of the Basal forebrain. It is a part of the telencephalon and is located in the anterior part of the brain. The Substantia Innominata is composed of both gray matter and white matter.

Anatomy

The Substantia Innominata is a part of the Basal forebrain and is located in the anterior part of the brain. It is composed of both gray matter and white matter. The gray matter is made up of neurons, while the white matter is made up of axons. The Substantia Innominata is located below the anterior commissure and above the optic tract.

Function

The Substantia Innominata plays a crucial role in the cholinergic system, which is involved in memory and learning. It is also involved in the regulation of sleep and wakefulness. The Substantia Innominata is also associated with the limbic system, which is involved in emotion, behavior, motivation, long-term memory, and olfaction.

Clinical significance

Damage to the Substantia Innominata can lead to a variety of neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In Alzheimer's disease, there is a significant loss of neurons in the Substantia Innominata, which leads to a decrease in the production of acetylcholine, a neurotransmitter that is crucial for memory and learning.

See also

• Basal forebrain
• Cholinergic system
• Alzheimer's disease

References

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  Substantia innominata MRI

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  Nucleus basalis of Meynert - very low magnification