Thrombin
Thrombin
Thrombin (/ˈθrɒmbɪn/), also known as Factor IIa, is a serine protease that plays a crucial role in the blood coagulation cascade. It is produced from its precursor, prothrombin, by the enzymatic action of prothrombinase.
Etymology
The term "thrombin" is derived from the Greek word "θρόμβος" (thrombos), meaning "clot", and the suffix "-in", which is used in biochemistry to denote a protein.
Function
Thrombin is a key enzyme in the blood coagulation process. It converts soluble fibrinogen into insoluble fibrin, which forms the structural basis of a blood clot. In addition, thrombin also activates Factor XIII, Factor V, and Factor VIII, further promoting clot formation.
Related Terms
- Prothrombin: The precursor to thrombin.
- Fibrinogen: A protein that is converted by thrombin into fibrin to form a blood clot.
- Fibrin: The insoluble protein that forms the structural basis of a blood clot.
- Factor XIII, Factor V, Factor VIII: Coagulation factors that are activated by thrombin to promote clot formation.
- Prothrombinase: The enzyme that converts prothrombin into thrombin.
See Also
External links
- Medical encyclopedia article on Thrombin
- Wikipedia's article - Thrombin
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski