Thrombopoiesis
Thrombopoiesis (pronounced: throm-bo-po-ee-sis) is the process by which blood platelets are produced in the body. This process is a part of hematopoiesis, the formation of blood cellular components.
Etymology
The term "Thrombopoiesis" is derived from the Greek words "Thrombos" meaning clot, and "poiesis" meaning to make.
Process
Thrombopoiesis begins in the bone marrow, where hematopoietic stem cells (HSCs) differentiate into megakaryocytes, large cells responsible for the production of platelets. This process is regulated by a hormone known as thrombopoietin (TPO), which is primarily produced in the liver and kidneys.
Once the megakaryocytes are fully mature, they extend protrusions known as proplatelets into the blood vessels. These proplatelets then break off into smaller fragments, which become the platelets that circulate in the blood.
Related Terms
- Hematopoiesis: The process of forming blood cellular components.
- Megakaryocyte: A large cell in the bone marrow that produces platelets.
- Thrombopoietin: A hormone that regulates the production of platelets.
- Platelets: Small blood cells that help the body form clots to stop bleeding.
See Also
External links
- Medical encyclopedia article on Thrombopoiesis
- Wikipedia's article - Thrombopoiesis
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