Toxic anterior segment syndrome
Toxic Anterior Segment Syndrome
Toxic anterior segment syndrome (TASS), pronounced /ˈtɒksɪk ænˈtɪərɪər ˈsɛgmənt ˈsɪndroʊm/, is a rare but severe inflammatory condition that affects the anterior segment of the eye, typically following intraocular surgery. The etymology of the term is derived from the Greek words "toxikon" (poison), "anterios" (before), "segmentum" (part), and "syndromos" (running together).
Definition
TASS is an acute, non-infectious inflammation of the anterior segment of the eye. This condition is typically characterized by symptoms such as pain, blurred vision, and sensitivity to light, which usually occur within 12 to 48 hours after intraocular surgery.
Causes
The exact cause of TASS is unknown, but it is believed to be related to a non-infectious inflammatory response to certain substances that may enter the eye during surgery. These substances can include detergents, enzymes, endotoxins, and other foreign bodies.
Treatment
Treatment for TASS typically involves the use of topical and systemic corticosteroids to reduce inflammation. In severe cases, additional surgical intervention may be required.
Related Terms
- Anterior Segment: The front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens.
- Intraocular Surgery: Any type of surgery that is performed inside the eye.
- Corticosteroids: A class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
See Also
- Postoperative Endophthalmitis: A serious inflammation of the interior of the eye which can occur after surgery.
- Uveitis: Inflammation of the uvea, the middle layer of the eye.
External links
- Medical encyclopedia article on Toxic anterior segment syndrome
- Wikipedia's article - Toxic anterior segment syndrome
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