Tylosin

Tylosin

Tylosin (pronounced: tie-low-sin) is a macrolide antibiotic that is used in veterinary medicine. It is produced by the Streptomyces fradiae strain of Actinobacteria.

Etymology

The term "Tylosin" is derived from the Greek word "tylos" meaning callus or knot, and "mykes" meaning fungus. This is in reference to the knotted fungal structures that produce the antibiotic.

Usage

Tylosin is primarily used in veterinary medicine to treat bacterial infections in a wide range of animals. It is particularly effective against certain types of Mycoplasma, Gram-positive bacteria, and some Gram-negative bacteria. It is also used as a growth promoter in some animals, such as chickens and pigs.

Mechanism of Action

Tylosin works by inhibiting the synthesis of protein in bacteria, thereby preventing their growth and reproduction. It binds to the 50S subunit of the bacterial ribosome, which prevents the addition of new amino acids to the growing peptide chain.

Related Terms

• Macrolide
• Antibiotic
• Streptomyces fradiae
• Actinobacteria
• Mycoplasma
• Gram-positive bacteria
• Gram-negative bacteria
• Ribosome

Side Effects

Like all antibiotics, Tylosin can cause side effects in some animals. These may include digestive upset, such as diarrhea or vomiting, and allergic reactions, such as hives or difficulty breathing. If these or any other side effects occur, the animal should be taken to a veterinarian immediately.

Precautions

Tylosin should not be used in animals with known hypersensitivity or allergy to it or to other macrolide antibiotics. It should also not be used in animals with severe liver disease, as it is metabolized by the liver and could potentially cause further damage.

External links

• Medical encyclopedia article on Tylosin
• Wikipedia's article - Tylosin

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