Vaso-occlusive crisis
Vaso-occlusive crisis
Vaso-occlusive crisis (pronunciation: vay-so-oh-kloo-siv kri-sis) is a common and painful complication of Sickle Cell Disease. It is also known as a sickle cell crisis.
Etymology
The term "vaso-occlusive" is derived from "vaso", a prefix from the Latin "vasculum" meaning vessel, and "occlusive", from the Latin "occludere" meaning to close up. "Crisis" comes from the Greek "krisis" meaning decision, referring to a crucial point in the progression of a disease.
Definition
A vaso-occlusive crisis occurs when the irregularly shaped red blood cells characteristic of sickle cell disease block blood vessels, preventing oxygen from reaching tissues and organs. This can cause severe pain and damage to the affected areas.
Symptoms
Symptoms of a vaso-occlusive crisis can vary depending on the area of the body affected, but often include severe pain, swelling, and fever. Other symptoms may include fatigue, rapid heart rate, and shortness of breath.
Causes
Vaso-occlusive crises are caused by the sickle-shaped red blood cells that are characteristic of sickle cell disease. These cells can become stuck in small blood vessels, blocking blood flow.
Treatment
Treatment for a vaso-occlusive crisis typically involves managing pain and preventing complications. This may include hydration, pain medication, and blood transfusions. In some cases, a drug called hydroxyurea may be used to reduce the number of crises.
Related Terms
External links
- Medical encyclopedia article on Vaso-occlusive crisis
- Wikipedia's article - Vaso-occlusive crisis
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