Wilhelm Uhthoff

German ophthalmologist

Wilhelm Uhthoff (31 July 1853 – 21 March 1927) was a notable German ophthalmologist known for his contributions to the understanding of neurological and visual disorders. His work primarily focused on the relationship between optic neuritis and multiple sclerosis.

Early Life and Education

Wilhelm Uhthoff was born in Klein Warin, Mecklenburg-Schwerin, Germany. He pursued his medical studies at the University of Berlin, where he developed a keen interest in ophthalmology. After completing his education, Uhthoff worked under several prominent physicians, which helped him refine his skills and knowledge in the field.

Career

Uhthoff began his career as an assistant at the University of Jena, where he worked in the ophthalmology clinic. His dedication and expertise soon led him to a professorship at the University of Breslau (now Wrocław, Poland), where he spent the majority of his career.

Wilhelm Uhthoff

During his tenure at Breslau, Uhthoff conducted extensive research on the effects of optic neuritis and its association with multiple sclerosis. He is best known for describing what is now called "Uhthoff's phenomenon," a temporary worsening of neurological symptoms, particularly visual disturbances, in patients with multiple sclerosis when they become overheated.

Uhthoff's Phenomenon

Uhthoff's phenomenon is characterized by a temporary decrease in visual acuity and other neurological functions in response to an increase in body temperature. This can occur due to physical exercise, fever, or exposure to hot environments. Uhthoff's observations were crucial in understanding the pathophysiology of multiple sclerosis and its impact on the optic nerve.

Legacy

Wilhelm Uhthoff's contributions to medicine, particularly in the field of neuro-ophthalmology, have had a lasting impact. His work laid the foundation for further research into the relationship between neurological disorders and visual symptoms. Uhthoff's phenomenon remains a significant consideration in the diagnosis and management of multiple sclerosis today.

Related Pages

• Optic neuritis
• Multiple sclerosis
• Neuro-ophthalmology
• University of Breslau