Zinc and the common cold

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Zinc and the Common Cold

Zinc supplement tablets

Zinc is an essential trace element that plays a vital role in the human body, including the immune system. It has been studied for its potential effects on the common cold, a viral infection of the upper respiratory tract.

Role of Zinc in the Immune System

Zinc is crucial for maintaining a healthy immune system. It is involved in various cellular processes, including cell division, protein synthesis, and the functioning of immune cells such as T cells and B cells. Zinc deficiency can lead to impaired immune function and increased susceptibility to infections.

Zinc and Cold Symptoms

Research has suggested that zinc may reduce the duration and severity of cold symptoms. The proposed mechanism is that zinc may inhibit the replication of rhinoviruses, the most common cause of the common cold. Zinc ions are thought to interfere with the virus's ability to attach to and penetrate the mucous membranes of the nasal cavity.

Forms of Zinc

Zinc is available in various forms, including zinc gluconate, zinc acetate, and zinc sulfate. These are often found in over-the-counter cold remedies such as lozenges and nasal sprays. The effectiveness of zinc supplements can vary depending on the formulation and dosage.

Recommended Dosage

The recommended dosage of zinc for treating the common cold is not universally agreed upon. However, studies have used doses ranging from 9 to 24 mg of elemental zinc per day. It is important to start zinc supplementation within 24 hours of the onset of symptoms for maximum effectiveness.

Side Effects and Precautions

While zinc is generally safe when taken in appropriate doses, excessive intake can lead to side effects such as nausea, a metallic taste in the mouth, and interference with the absorption of other essential minerals like copper. Long-term use of high doses of zinc is not recommended.

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Contributors: Prab R. Tumpati, MD