CFP-10
CFP-10
CFP-10 (pronounced as /ˈsiːˈefˈpiːˈten/), also known as Culture Filtrate Protein 10, is a protein that is encoded by the cfp10 gene in the Mycobacterium tuberculosis complex. It is a secreted protein that plays a crucial role in the pathogenesis of tuberculosis.
Etymology
The term CFP-10 is an acronym derived from Culture Filtrate Protein 10. The number 10 refers to the molecular weight of the protein, which is approximately 10 kDa.
Function
CFP-10 is a secreted protein that is involved in the virulence of Mycobacterium tuberculosis. It forms a 1:1 complex with another secreted protein, ESAT-6, and this complex is thought to disrupt the host cell membrane, allowing the bacteria to escape from the phagosome and replicate in the cytoplasm.
Related Terms
- ESAT-6: A secreted protein that forms a complex with CFP-10, contributing to the virulence of Mycobacterium tuberculosis.
- Mycobacterium tuberculosis: The bacterium that causes tuberculosis, which secretes CFP-10.
- Tuberculosis: A disease caused by Mycobacterium tuberculosis, which is associated with the secretion of CFP-10.
See Also
External links
- Medical encyclopedia article on CFP-10
- Wikipedia's article - CFP-10
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