Eosinophilic granuloma
Eosinophilic Granuloma
Eosinophilic granuloma (pronunciation: ee-oh-sin-oh-fil-ik gran-yuh-loh-muh) is a rare disorder that is part of the Langerhans cell histiocytosis (LCH) spectrum. It is characterized by the proliferation of Langerhans cells, which are a type of white blood cell.
Etymology
The term "eosinophilic granuloma" is derived from the Greek words "eosin," meaning "dawn-colored," and "philos," meaning "loving," referring to the pink color of the granuloma under a microscope. "Granuloma" is derived from the Latin "granulum," meaning "small grain," referring to the granular appearance of the lesion.
Symptoms
Symptoms of eosinophilic granuloma can vary greatly depending on the location and extent of the lesion. Common symptoms include pain, swelling, and in some cases, pathological fracture. If the lesion is in the lung, symptoms may include cough, chest pain, and difficulty breathing.
Diagnosis
Diagnosis of eosinophilic granuloma typically involves a combination of medical history, physical examination, imaging studies such as X-ray or MRI, and biopsy of the lesion. The definitive diagnosis is made by identifying characteristic Langerhans cells in the biopsy specimen.
Treatment
Treatment of eosinophilic granuloma depends on the location and extent of the disease. Options may include observation, surgery, radiation therapy, and/or chemotherapy. In some cases, the lesion may resolve spontaneously.
Related Terms
External links
- Medical encyclopedia article on Eosinophilic granuloma
- Wikipedia's article - Eosinophilic granuloma
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