Estradiol hexahydrobenzoate

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Estradiol hexahydrobenzoate (pronunciation: es-tra-DYE-ol hex-a-hydro-BEN-zo-ate) is a synthetic, steroidal estrogen that is a derivative of estradiol, the primary female sex hormone. It is used in hormone therapy and for various other medical purposes.

Etymology

The term "estradiol" is derived from estrus (Latin for "gadfly" or "frenzy"), -diol (a chemical term denoting an alcohol), and hexahydrobenzoate (indicating the presence of a hexahydrobenzoic acid ester group).

Pharmacology

Estradiol hexahydrobenzoate is a prodrug of estradiol and is converted into estradiol in the body. It is used in medicine as a component of some formulations of hormone replacement therapy for menopausal symptoms. It is also used in the treatment of low estrogen levels, prostate cancer, and in feminizing hormone therapy for transgender women.

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