Flomoxef
Flomoxef
Flomoxef (pronounced: flo-mox-ef) is a oxacephem antibiotic that is used in the treatment of various bacterial infections. It is also known by its brand name, Flumarin.
Etymology
The term "Flomoxef" is derived from its chemical structure, which is a combination of "fluoro", "methyl", and "oxacephem". The "fluoro" and "methyl" parts refer to the presence of fluorine and methyl groups in the molecule, while "oxacephem" is a type of cephalosporin antibiotic that contains an oxygen atom in its structure.
Usage
Flomoxef is used to treat a wide range of bacterial infections, including those caused by Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. It is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) and penicillin-resistant Streptococcus pneumoniae (PRSP).
Mechanism of Action
Flomoxef works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It binds to penicillin-binding proteins (PBPs) in the bacterial cell wall, which are essential for cell wall synthesis. This binding inhibits the cross-linking of peptidoglycan chains, a critical step in cell wall biosynthesis.
Side Effects
Common side effects of Flomoxef include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause serious side effects such as anaphylaxis, a severe allergic reaction.
Related Terms
- Oxacephem
- Antibiotic
- Staphylococcus aureus
- Escherichia coli
- Klebsiella pneumoniae
- Methicillin-resistant Staphylococcus aureus
- Penicillin-resistant Streptococcus pneumoniae
- Anaphylaxis
External links
- Medical encyclopedia article on Flomoxef
- Wikipedia's article - Flomoxef
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