Genetic architecture
Genetic Architecture
Genetic architecture refers to the underlying genetic basis of a phenotypic trait and its variance. It encompasses the number and relative locations of genes involved, the allelic effects and their interactions (epistasis), and the interaction between genes and the environment (Gene-environment interaction).
Pronunciation
Genetic: /dʒɪˈnɛtɪk/ Architecture: /ɑːrˈkɪtɛktʃər/
Etymology
The term "genetic" is derived from the Greek word "genetikos" meaning "genitive" and "genes" meaning "born". "Architecture" comes from the Latin "architectura", from the Greek "arkhitekton", meaning "master builder".
Related Terms
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Phenotype: The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment.
- Genotype: The genetic constitution of an individual organism.
- Quantitative trait locus (QTL): A section of DNA (the locus) which correlates with variation in a phenotype (the quantitative trait).
- Polygenic inheritance: The inheritance of traits such as skin color, eye color, and hair color, that are determined by more than one gene.
See Also
External links
- Medical encyclopedia article on Genetic architecture
- Wikipedia's article - Genetic architecture
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