International Normalized Ratio
International Normalized Ratio (INR) is a laboratory measurement used in medicine to assess the blood's ability to clot. It is most commonly used to monitor the effects of anticoagulant therapy in patients with conditions such as atrial fibrillation or deep vein thrombosis.
Pronunciation
The International Normalized Ratio is pronounced as /ɪntəˈnaʃənəl ˈnɔːrməlaɪzd ˈreɪʃioʊ/.
Etymology
The term "International Normalized Ratio" was coined in the late 20th century. It is derived from the method used to standardize the results of prothrombin time tests, which measure the time it takes for blood to clot. The "international" aspect refers to the global standardization of these results, while "normalized ratio" refers to the mathematical calculation used to adjust the results for variations in the sensitivity of the thromboplastin used in the test.
Related Terms
- Prothrombin time (PT): A test that measures how long it takes blood to clot.
- Thromboplastin: A substance present in blood that contributes to clotting.
- Anticoagulant: A medication that prevents blood from clotting.
- Atrial fibrillation: A heart condition characterized by an irregular and often rapid heart rate.
- Deep vein thrombosis: A condition in which a blood clot forms in one of the deep veins of the body, usually in the legs.
See Also
External links
- Medical encyclopedia article on International Normalized Ratio
- Wikipedia's article - International Normalized Ratio
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