Lathyrism

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Lathyrism (pronounced: la-thy-rism, /ləˈθaɪrɪzəm/) is a medical condition caused by the excessive consumption of certain species of the Lathyrus genus, particularly Lathyrus sativus (also known as grass pea or chickling vetch).

Etymology

The term "Lathyrism" is derived from the Greek word "lathyros" which means "pea". It was first used in the medical literature in the late 19th century.

Symptoms

The symptoms of Lathyrism can vary, but often include muscle weakness, paralysis, and numbness. In severe cases, it can lead to permanent paralysis and disability.

Causes

Lathyrism is caused by the excessive consumption of certain species of the Lathyrus genus, particularly Lathyrus sativus. These plants contain a neurotoxic amino acid called ODAP (β-N-oxalyl-L-α,β-diaminopropionic acid), which is believed to be the primary cause of the disease.

Prevention and Treatment

Prevention of Lathyrism involves avoiding the excessive consumption of Lathyrus species. Treatment typically involves managing the symptoms and may include physical therapy for muscle weakness and paralysis.

Related Terms

  • Lathyrus - A genus of flowering plants in the legume family, some species of which can cause Lathyrism when consumed in large amounts.
  • ODAP - A neurotoxic amino acid found in certain species of the Lathyrus genus, believed to be the primary cause of Lathyrism.
  • Neurotoxin - A toxin that affects the nervous system, often causing symptoms such as muscle weakness and paralysis.

External links

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