Netoglitazone
Netoglitazone
Netoglitazone (pronunciation: /nɛtoʊgliˈtæzoʊn/) is a thiazolidinedione derivative used in the treatment of Type 2 diabetes. It is an antidiabetic agent that functions as an insulin sensitizer.
Etymology
The term "Netoglitazone" is derived from the chemical structure of the drug, which is a derivative of the thiazolidinedione class. The prefix "neto-" is a modification of the chemical name "n-ethyl", referring to the ethyl group present in the molecule. The suffix "-glitazone" is common to all drugs in the thiazolidinedione class, indicating their shared mechanism of action.
Mechanism of Action
Netoglitazone works by binding to the peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor that regulates the transcription of genes involved in glucose and lipid metabolism. This binding increases the sensitivity of cells to insulin, allowing more glucose to be taken up from the bloodstream and lowering blood glucose levels.
Related Terms
- Thiazolidinedione: A class of drugs to which netoglitazone belongs. They are used to treat type 2 diabetes by increasing the sensitivity of cells to insulin.
- Insulin: A hormone produced by the pancreas that regulates the amount of glucose in the blood. Netoglitazone increases the sensitivity of cells to insulin.
- Peroxisome proliferator-activated receptor gamma (PPARγ): A nuclear receptor that netoglitazone binds to, increasing the sensitivity of cells to insulin.
See Also
External links
- Medical encyclopedia article on Netoglitazone
- Wikipedia's article - Netoglitazone
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