Notch signaling pathway
Notch Signaling Pathway
The Notch signaling pathway is a highly conserved cell communication mechanism that plays a vital role in cell differentiation, cell proliferation, and apoptosis.
Pronunciation
The term "Notch signaling pathway" is pronounced as /ˈnɒtʃ ˈsɪɡnəlɪŋ ˈpæθweɪ/.
Etymology
The term "Notch" was first used in 1917 by Thomas Hunt Morgan, who noticed notched wings in a strain of fruit flies. The term "signaling pathway" refers to the series of chemical reactions that lead to a certain response in a cell.
Function
The Notch signaling pathway is involved in the regulation of many developmental processes, including neurogenesis, somitogenesis, and angiogenesis. It is also implicated in several diseases, including cancer, Alzheimer's disease, and cardiovascular disease.
Related Terms
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