Pyronaridine

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Pyronaridine

Pyronaridine (pronunciation: py-ro-nar-di-ne) is an antimalarial drug used in the treatment of malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Pyronaridine is often used in combination with artesunate, another antimalarial drug, in a treatment known as Pyronaridine-Artesunate.

Etymology

The term "Pyronaridine" is derived from the chemical name 4-[(10Z)-3-(dibutylamino)-10-[(4-methoxyphenyl)imino]-7-(pyridin-4-yl)-2,3,5,10-tetrahydro-1H,4H,10H-[1,3]dioxino[6,5-b:5',6'-g]quinolin-1-yl]phenol. The name is a combination of its chemical structure and its medicinal use.

Usage

Pyronaridine is used in the treatment of malaria, specifically for the treatment of Plasmodium falciparum and Plasmodium vivax infections. It is often used in combination with artesunate in a treatment known as Pyronaridine-Artesunate. This combination therapy is recommended by the World Health Organization for the treatment of uncomplicated P. falciparum malaria.

Related Terms

  • Antimalarial drug: A type of medication used in the prevention and treatment of malaria.
  • Artesunate: An antimalarial drug often used in combination with pyronaridine.
  • Malaria: A disease caused by a plasmodium parasite, transmitted by the bite of infected mosquitoes.
  • Plasmodium falciparum: A species of parasitic protozoa that causes malaria in humans.
  • Plasmodium vivax: Another species of parasitic protozoa that causes malaria in humans.
  • World Health Organization: A specialized agency of the United Nations responsible for international public health.

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