Rifampicin/isoniazid/pyrazinamide
Rifampicin/Isoniazid/Pyrazinamide
Rifampicin/Isoniazid/Pyrazinamide (pronunciation: rih-fam-PIN/eye-so-NYE-a-zid/py-ra-ZIN-a-mide) is a combination medication used primarily in the treatment of tuberculosis.
Etymology
The names of the individual drugs in this combination have their roots in various languages. 'Rifampicin' is derived from the name of the bacteria Rifamycin, from which it was first isolated. 'Isoniazid' is an acronym for isonicotinic acid hydrazide, the chemical name for the drug. 'Pyrazinamide' is named for its chemical structure, which includes a pyrazine ring.
Usage
Rifampicin/Isoniazid/Pyrazinamide is used in the initial phase of tuberculosis treatment. It is a first-line treatment, meaning it is the preferred method of treatment when tuberculosis is diagnosed. The combination of these three drugs is designed to attack the tuberculosis bacteria in different ways, reducing the chance of the bacteria developing resistance to the treatment.
Related Terms
- Rifampicin: An antibiotic used to treat several types of bacterial infections, including tuberculosis.
- Isoniazid: An antibiotic specifically used for the treatment of tuberculosis.
- Pyrazinamide: An antibiotic that is used with other medications to treat tuberculosis.
- Tuberculosis: An infectious disease usually caused by Mycobacterium tuberculosis bacteria.
External links
- Medical encyclopedia article on Rifampicin/isoniazid/pyrazinamide
- Wikipedia's article - Rifampicin/isoniazid/pyrazinamide
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