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• C-ABL
  |Term=c-ABL |Short definition=c-ABL - An enzyme involved in many cellular processes such as B. cell division is
  604 bytes (92 words) - 22:10, 10 January 2023
• ABL (gene)
  == ABL (gene) == The '''ABL''' gene, also known as '''ABL1''' or '''c-ABL''', is a gene found in humans and many other organisms. It is located on ch
  2 KB (275 words) - 23:19, 3 February 2024
• Bcr-abl
  == Bcr-abl == ...anslocation: the '''[[Breakpoint Cluster Region|BCR]]''' gene and the '''[[ABL proto-oncogene 1, non-receptor tyrosine kinase|ABL1]]''' gene.
  2 KB (293 words) - 22:51, 4 February 2024
• BCR-ABL
  ...ation, specifically the [[Philadelphia chromosome]] translocation. The BCR-ABL gene is associated with certain types of [[Leukemia]], including [[Chronic ...CR and ABL genes also swap portions, resulting in the formation of the BCR-ABL fusion gene.
  1 KB (192 words) - 22:44, 14 February 2024
• BCR-ABL fusion gene
  |Term=BCR-ABL fusion gene ...e on chromosome 9 joins with the BCR gene on chromosome 22 to form the BCR-ABL fusion gene. 
  868 bytes (133 words) - 01:25, 8 January 2023

Page text matches

• C-ABL
  |Term=c-ABL |Short definition=c-ABL - An enzyme involved in many cellular processes such as B. cell division is
  604 bytes (92 words) - 22:10, 10 January 2023
• BCR-ABL fusion gene
  |Term=BCR-ABL fusion gene ...e on chromosome 9 joins with the BCR gene on chromosome 22 to form the BCR-ABL fusion gene. 
  868 bytes (133 words) - 01:25, 8 January 2023
• ABL (gene)
  == ABL (gene) == The '''ABL''' gene, also known as '''ABL1''' or '''c-ABL''', is a gene found in humans and many other organisms. It is located on ch
  2 KB (275 words) - 23:19, 3 February 2024
• BCR-ABL
  ...ation, specifically the [[Philadelphia chromosome]] translocation. The BCR-ABL gene is associated with certain types of [[Leukemia]], including [[Chronic ...CR and ABL genes also swap portions, resulting in the formation of the BCR-ABL fusion gene.
  1 KB (192 words) - 22:44, 14 February 2024
• ABL1
  #REDIRECT [[ABL (gene)]]
  24 bytes (3 words) - 19:27, 3 February 2024
• Bcr-abl
  == Bcr-abl == ...anslocation: the '''[[Breakpoint Cluster Region|BCR]]''' gene and the '''[[ABL proto-oncogene 1, non-receptor tyrosine kinase|ABL1]]''' gene.
  2 KB (293 words) - 22:51, 4 February 2024
• Fusion protein
  ...L gene found in some types of leukemia is a fusion gene that forms the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laborator
  922 bytes (142 words) - 05:13, 9 January 2023
• Radotinib
  ...(CML). It is a second-generation drug that specifically targets the [[BCR-ABL]] fusion protein, a characteristic feature of CML. Radotinib inhibits the activity of BCR-ABL tyrosine kinase, an abnormal enzyme produced by the cells of patients with
  2 KB (194 words) - 23:19, 5 February 2024
• T315I mutation
  |Short definition=T315I mutation - type of mutation (change) in the BCR-ABL fusion protein, an abnormal protein that occurs in most people with chronic T315I mutation - type of mutation (change) in the BCR-ABL fusion protein, an abnormal protein that occurs in most people with chronic
  918 bytes (137 words) - 16:55, 13 January 2023
• Chronic Myelogenous Leukemia
  ...ells (except lymphocytes). This change forms an abnormal gene called [[BCR-ABL]], which turns the cell into a CML cell. The leukemia cells grow and divide ...st or bone marrow biopsy that shows the [[Philadelphia chromosome]] or BCR-ABL gene.
  2 KB (260 words) - 04:28, 12 February 2024
• Saracatinib
  ...s a small molecule [[inhibitor]] that targets [[Src family kinases]] and [[ABL kinases]]. It is primarily used in the research and treatment of various [[ * [[ABL kinases]]: A group of proteins that are involved in regulating the cell cyc
  1 KB (190 words) - 00:18, 7 February 2024
• Nilotinib
  ...ancer cells to divide and grow. It binds to and inhibits the protein [[BCR-ABL]], which is found in CML cells. This helps to stop or slow the spread of ca * [[BCR-ABL]]
  1 KB (193 words) - 20:11, 5 February 2024
• Asciminib
  ...t suitable. Asciminib works by blocking the action of a protein called BCR-ABL, which is responsible for the growth of cancer cells. * [[BCR-ABL]]: A fusion gene that is formed as a result of the Philadelphia chromosome
  2 KB (246 words) - 16:28, 5 February 2024
• Gleevec
  ...ther diseases and cancers. Gleevec blocks certain proteins made by the BCR-ABL, PDGFR, or c-KITO oncogene, which can help prevent cancer cells from growin
  751 bytes (105 words) - 05:28, 9 January 2023
• Tasigna
  ...eing studied in the treatment of other types of cancer. Tasigna blocks BCR-ABL and other proteins that can help prevent cancer cells from growing. It's a
  788 bytes (111 words) - 05:44, 13 January 2023
• Nilotinib hydrochloride monohydrate
  ...t of other types of cancer. Nilotinib hydrochloride monohydrate blocks BCR-ABL and other proteins that may help prevent cancer cells from growing. It's a
  872 bytes (117 words) - 17:42, 10 January 2023
• Bosutinib
  ...ng studied in the treatment of other types of cancer. Bosutinib blocks BCR-ABL and other proteins that can help prevent cancer cells from growing. It's a
  910 bytes (130 words) - 01:31, 8 January 2023
• Bosulif
  ...eing studied in the treatment of other types of cancer. Bosulif blocks BCR-ABL and other proteins that can prevent cancer cells from growing. It's a type
  895 bytes (131 words) - 21:11, 10 January 2023
• STI571
  ...other diseases and cancers. STI571 blocks certain proteins made by the BCR-ABL, PDGFR, or c-KIT oncogene, which may help prevent cancer cells from growing
  985 bytes (142 words) - 14:01, 12 January 2023
• Scemlix
  ...studied in the treatment of other types of cancer. Scemblix blocks the BCR-ABL fusion protein, which can help prevent cancer cells from growing and kill t
  1 KB (156 words) - 08:06, 13 January 2023

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