Steroidogenesis inhibitor
Steroidogenesis Inhibitor
A Steroidogenesis Inhibitor (pronunciation: ster-oid-o-gen-esis in-hib-it-or) is a type of drug that inhibits the production of steroids in the body. These drugs are often used in the treatment of various endocrine disorders and cancers that are dependent on steroids.
Etymology
The term "Steroidogenesis Inhibitor" is derived from the words "steroid", "genesis" (meaning creation), and "inhibitor". "Steroid" is a type of organic compound that is naturally produced in the body. "Genesis" is a Greek word that means "origin" or "creation". "Inhibitor" refers to a substance that slows down or stops a chemical reaction.
Mechanism of Action
Steroidogenesis inhibitors work by blocking the enzymes that are involved in the production of steroids. These enzymes include CYP17A1, CYP19A1, and CYP11B1. By inhibiting these enzymes, the drugs can reduce the levels of steroids in the body.
Uses
Steroidogenesis inhibitors are used in the treatment of a variety of conditions. These include Cushing's syndrome, prostate cancer, and breast cancer. They can also be used to treat polycystic ovary syndrome (PCOS) and congenital adrenal hyperplasia (CAH).
Side Effects
Like all drugs, steroidogenesis inhibitors can cause side effects. These can include nausea, vomiting, diarrhea, and fatigue. In some cases, the drugs can also cause adrenal insufficiency.
Related Terms
- CYP17A1
- CYP19A1
- CYP11B1
- Cushing's syndrome
- Prostate cancer
- Breast cancer
- Polycystic ovary syndrome
- Congenital adrenal hyperplasia
- Adrenal insufficiency
External links
- Medical encyclopedia article on Steroidogenesis inhibitor
- Wikipedia's article - Steroidogenesis inhibitor
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