Subventricular zone

From WikiMD.org
Jump to navigation Jump to search

Subventricular Zone

The Subventricular Zone (SVZ), pronounced as /sʌbˌvɛnˈtrɪkjʊlər zoʊn/, is a region in the brain where neurogenesis, the process of generating new neurons, occurs. The term "subventricular" is derived from the Latin words "sub" meaning "under" and "ventriculus" meaning "small cavity or chamber", referring to its location beneath the ventricles of the brain.

Structure

The Subventricular Zone is located in the walls of the lateral ventricles. It is composed of four layers: the ependymal layer, the subependymal layer, the intermediate zone, and the ribbon. Each of these layers has a distinct population of cells and contributes to the overall function of the SVZ.

Function

The primary function of the Subventricular Zone is to serve as a source of neural stem cells in the process of neurogenesis. These neural stem cells can differentiate into various types of brain cells, including neurons, astrocytes, and oligodendrocytes. The SVZ is one of the few areas in the adult brain where neurogenesis is known to occur.

Clinical Significance

Alterations in the Subventricular Zone have been associated with various neurological disorders, including Parkinson's disease, Alzheimer's disease, and stroke. Research is ongoing to understand the potential therapeutic applications of SVZ neurogenesis in these conditions.

See Also

References


External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski