2-Methoxyestradiol
2-Methoxyestradiol
2-Methoxyestradiol (pronounced as two-meth-oxy-es-tra-dye-ol) is a natural metabolite of estrogen that is known to inhibit the growth of rapidly dividing cells and angiogenesis. It is also known as 2-ME or 2-ME2.
Etymology
The term "2-Methoxyestradiol" is derived from its chemical structure. The "2-Methoxy" part refers to the methoxy group (-OCH3) attached at the 2nd position of the estradiol molecule. "Estradiol" is a type of estrogen, a group of hormones that play an important role in the reproductive system.
Function
2-Methoxyestradiol has been found to have anti-proliferative and anti-angiogenic properties, meaning it can inhibit the growth of cells and the formation of new blood vessels, respectively. These properties make it a potential candidate for cancer treatment, particularly in cases where the cancer is characterized by rapid cell division and angiogenesis.
Related Terms
- Estrogen: A group of hormones that play an important role in the reproductive system.
- Angiogenesis: The formation of new blood vessels.
- Anti-angiogenic: Referring to the ability to inhibit the formation of new blood vessels.
- Anti-proliferative: Referring to the ability to inhibit the growth of cells.
See Also
External links
- Medical encyclopedia article on 2-Methoxyestradiol
- Wikipedia's article - 2-Methoxyestradiol
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