2-methoxyestradiol
2-Methoxyestradiol
2-Methoxyestradiol (pronounced as two-meth-oxy-es-tra-diol) is a natural metabolite of estrogen that is known to inhibit the growth of rapidly dividing cells and angiogenesis. It is also known by its chemical name, 2-MeOE2.
Etymology
The term 2-Methoxyestradiol is derived from its chemical structure. The "2-Methoxy" part refers to the methoxy group (-OCH3) attached at the 2nd position of the estradiol molecule. "Estradiol" is a type of estrogen, a group of hormones that play an important role in the reproductive system.
Function
2-Methoxyestradiol has been found to have anti-proliferative and anti-angiogenic properties, meaning it can inhibit the growth of cells and the formation of new blood vessels, respectively. These properties make it a potential candidate for cancer treatment, particularly in inhibiting the growth of tumors.
Related Terms
- Estrogen: A group of hormones that play an important role in the reproductive system.
- Metabolite: A substance formed in or necessary for metabolism.
- Angiogenesis: The formation of new blood vessels.
- Tumor: An abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function.
See Also
External links
- Medical encyclopedia article on 2-methoxyestradiol
- Wikipedia's article - 2-methoxyestradiol
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