25G-NBOMe

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25G-NBOMe

Chemical structure of 25G-NBOMe

25G-NBOMe is a synthetic psychedelic compound that belongs to the NBOMe series. It is a derivative of the phenethylamine 2C-G and is known for its potent hallucinogenic effects. The compound is part of a class of substances that are often used in psychedelic research and recreational settings.

Chemical Structure and Properties

25G-NBOMe is chemically known as 2-(4-bromo-3,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine. It is a derivative of the 2C family of phenethylamines, specifically 2C-G, with the addition of a 2-methoxybenzyl group to the nitrogen atom, which is characteristic of the NBOMe series.

The compound is typically synthesized in a laboratory setting and is known for its high potency, requiring only microgram doses to achieve its effects. This potency is due to its high affinity for the 5-HT2A receptor, which is a common target for psychedelic compounds.

Pharmacology

25G-NBOMe acts primarily as a partial agonist at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound may also interact with other serotonin receptors, contributing to its overall pharmacological profile.

The effects of 25G-NBOMe can include visual and auditory hallucinations, altered perception of time and space, and changes in mood and thought processes. These effects are similar to those produced by other psychedelics such as LSD and psilocybin.

Usage and Effects

Due to its potency, 25G-NBOMe is typically administered in very small doses, often via blotter paper or as a liquid solution. Users report a range of effects, including intense visual hallucinations, euphoria, and altered sensory perception.

The onset of effects usually occurs within 30 to 90 minutes after administration, with the peak effects lasting several hours. The total duration of the experience can vary, but it is generally in the range of 6 to 10 hours.

Safety and Legal Status

The safety profile of 25G-NBOMe is not well-established, and there have been reports of adverse effects, particularly at higher doses. These can include vasoconstriction, tachycardia, hypertension, and in some cases, severe psychological distress.

Legally, 25G-NBOMe is classified as a controlled substance in many countries due to its potential for abuse and lack of accepted medical use. It is important for users to be aware of the legal status of this compound in their jurisdiction.

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Contributors: Prab R. Tumpati, MD