25iP-NBOMe

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25iP-NBOMe

Chemical structure of 25iP-NBOMe

25iP-NBOMe is a synthetic psychedelic compound belonging to the NBOMe class. It is a derivative of the phenethylamine 2C-iP and is known for its potent hallucinogenic effects. The compound is part of a larger group of substances that have been explored for their psychoactive properties.

Chemical Structure and Properties

25iP-NBOMe is chemically related to other NBOMe compounds, such as 25I-NBOMe and 25C-NBOMe. The structure of 25iP-NBOMe includes a methoxybenzyl group attached to the nitrogen of the phenethylamine backbone, which is characteristic of the NBOMe series. This modification significantly increases the compound's affinity for the 5-HT2A receptor, which is primarily responsible for its psychedelic effects.

Pharmacology

The primary mechanism of action for 25iP-NBOMe is its agonism of the 5-HT2A receptor, a subtype of the serotonin receptor. This interaction is believed to be responsible for the hallucinogenic effects experienced by users. The compound may also interact with other serotonin receptor subtypes, contributing to its overall pharmacological profile.

Effects

Users of 25iP-NBOMe report a range of effects, including visual and auditory hallucinations, altered perception of time, and changes in mood and cognition. The intensity and duration of these effects can vary depending on the dose and individual sensitivity. As with other NBOMe compounds, there is a risk of adverse effects, particularly at higher doses.

Safety and Legal Status

The safety profile of 25iP-NBOMe is not well-established, and there have been reports of severe adverse reactions, including vasoconstriction, tachycardia, and seizures. Due to these risks, the compound is often classified as a research chemical and is not approved for human consumption in many jurisdictions. The legal status of 25iP-NBOMe varies by country, with some places having specific bans on NBOMe compounds.

Related Compounds

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Contributors: Prab R. Tumpati, MD