Adenosine A2A receptor
Adenosine A2A receptor
The Adenosine A2A receptor (pronounced as: ad-uh-no-seen ay-two-ay ree-sep-tor) is a type of protein that is encoded in humans by the ADORA2A gene. It is a subtype of the adenosine receptor family.
Etymology
The term "Adenosine A2A receptor" is derived from the adenosine molecule, which is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule. The "A2A" refers to the specific subtype of the receptor.
Function
The Adenosine A2A receptor is predominantly found in the brain, specifically in the basal ganglia region. It plays a crucial role in the regulation of coronary blood flow and myocardial oxygen consumption. It is also involved in the regulation of neurotransmitter release, and is thought to play a role in the pathophysiology of Parkinson's disease and schizophrenia.
Related Terms
- Adenosine: A nucleoside and a neurotransmitter in the brain, which plays a crucial role in energy transfer.
- Receptor (biochemistry): A protein molecule that receives chemical signals from outside a cell.
- Basal ganglia: A group of structures in the brain that control movement and behavior.
- Parkinson's disease: A long-term degenerative disorder of the nervous system that mainly affects the motor system.
- Schizophrenia: A mental disorder characterized by abnormal behavior, strange speech, and a decreased ability to understand reality.
See Also
External links
- Medical encyclopedia article on Adenosine A2A receptor
- Wikipedia's article - Adenosine A2A receptor
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