Adenosine deaminase

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Adenosine Deaminase

Adenosine deaminase (pronounced: a-den-o-seen dee-am-in-ase) is an enzyme that plays a crucial role in purine metabolism. It is involved in the breakdown and utilization of adenosine and deoxyadenosine, which are components of DNA and RNA.

Etymology

The term "adenosine deaminase" is derived from the name of the molecule it acts upon, adenosine, and the process it facilitates, deamination. "Adenosine" is a combination of "adenine" and "ribose," the two components of the molecule. "Deaminase" comes from "deamination," the removal of an amino group.

Function

Adenosine deaminase is primarily found in lymphocytes and monocytes, where it catalyzes the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine respectively. This process is essential for the breakdown of these molecules, preventing their harmful accumulation in the body.

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