Polyostotic fibrous dysplasia

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Polyostotic fibrous dysplasia (pronunciation: pol-ee-oh-STOT-ik FIB-rus dis-PLAY-zee-uh) is a rare bone disease that affects multiple bones in the body.

Etymology

The term Polyostotic fibrous dysplasia is derived from the Greek words poly meaning many, osteon meaning bone, fibrous referring to the fibrous tissue, and dysplasia meaning abnormal growth or development.

Definition

Polyostotic fibrous dysplasia is a condition where normal bone and marrow are replaced by fibrous tissue and randomly distributed, poorly formed bone trabeculae. This can lead to fractures and deformity of the affected bones.

Symptoms

The symptoms of polyostotic fibrous dysplasia can vary greatly from person to person. They may include bone pain, bone deformities, fractures, and endocrine abnormalities such as precocious puberty in girls.

Related Terms

  • Fibrous dysplasia: A bone disease characterized by areas of abnormal growth or lesions in one or more bones.
  • Monostotic fibrous dysplasia: A variant of fibrous dysplasia where only one bone is affected.
  • McCune-Albright syndrome: A complex genetic disorder that affects the skin, bones, and endocrine system. Polyostotic fibrous dysplasia is often associated with this syndrome.
  • Osteomalacia: A condition characterized by softening of the bones caused by impaired bone metabolism.
  • Osteoblast: A type of cell that is responsible for bone formation.
  • Osteoclast: A type of cell that breaks down bone tissue.

See Also

References


External links

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