Alpha-blocker
Alpha-blocker
Alpha-blockers (pronounced: al-fuh blok-erz), also known as alpha-adrenergic antagonists or alpha-adrenoceptor antagonists, are a class of medications that are primarily used to treat certain medical conditions involving the cardiovascular system and prostate gland.
Etymology
The term "alpha-blocker" is derived from the class of receptors they act upon, known as alpha adrenergic receptors. The term "blocker" refers to the mechanism of action of these medications, which is to block or inhibit the action of certain chemicals in the body.
Usage
Alpha-blockers are commonly used in the treatment of high blood pressure (hypertension), benign prostatic hyperplasia (BPH), and certain vascular conditions. They work by relaxing the muscles in the walls of blood vessels and the prostate, allowing for easier blood flow and urine flow.
Types of Alpha-blockers
There are two main types of alpha-blockers: non-selective and selective. Non-selective alpha-blockers, such as phenoxybenzamine and phentolamine, can block both alpha-1 and alpha-2 receptors. Selective alpha-blockers, such as doxazosin, terazosin, and tamsulosin, primarily block alpha-1 receptors.
Side Effects
Common side effects of alpha-blockers include dizziness, headache, and fatigue. Less common but more serious side effects can include a rapid heart rate (tachycardia), low blood pressure (hypotension), and fainting (syncope).
See Also
External links
- Medical encyclopedia article on Alpha-blocker
- Wikipedia's article - Alpha-blocker
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