Anti-Cancer Drugs
Anti-Cancer Drugs are a category of pharmaceutical drugs specifically designed and administered to combat various forms of cancer. These drugs, also known as chemotherapy, work by interfering with the cancer cell's ability to divide and reproduce.
Types of Anti-Cancer Drugs
There are several types of anti-cancer drugs, each with a unique mechanism of action and specific types of cancer they are most effective against.
- Alkylating Agents: These drugs work by damaging the DNA of the cancer cell, preventing it from reproducing. Examples include cyclophosphamide and ifosfamide.
- Antimetabolites: These drugs mimic nutrients that the cancer cells need to grow, tricking the cells into consuming them and subsequently inhibiting their ability to reproduce. Examples include methotrexate and 5-fluorouracil.
- Antitumor Antibiotics: These drugs interfere with the enzymes involved in DNA replication. Examples include doxorubicin and bleomycin.
- Topoisomerase Inhibitors: These drugs interfere with the topoisomerase enzyme, which cancer cells need to divide. Examples include irinotecan and topotecan.
- Mitotic Inhibitors: These drugs prevent cancer cells from undergoing mitosis, or cell division. Examples include paclitaxel and vinblastine.
Side Effects
Like all pharmaceutical drugs, anti-cancer drugs can have side effects. These can range from mild to severe and may include nausea, vomiting, hair loss, fatigue, and anemia. It's important for patients to discuss potential side effects with their healthcare provider before starting treatment.
Future Developments
Research into new anti-cancer drugs is ongoing, with many promising developments on the horizon. These include immunotherapy drugs, which boost the body's own immune system to fight cancer, and targeted therapy drugs, which specifically target cancer cells while leaving healthy cells untouched.
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Contributors: Prab R. Tumpati, MD