Aristolochic acid
Aristolochic Acid
Aristolochic acid (pronunciation: /ˌærɪstəˈlɒkɪk ˈæsɪd/) is a carcinogenic, mutagenic, and nephrotoxic compound commonly found in the Aristolochia and Asarum plant species.
Etymology
The term "Aristolochic acid" is derived from the Greek words "aristos" (best) and "locheia" (childbirth), referring to the historical use of Aristolochia species in childbirth. The suffix "-ic" is added to denote its acidic properties.
Description
Aristolochic acid is a mixture of structurally related nitrophenanthrene carboxylic acids. It is known for its toxic effects on the kidneys and its carcinogenic effects on the urinary tract. The International Agency for Research on Cancer (IARC) classifies Aristolochic acid as a Group 1 carcinogen, meaning it is carcinogenic to humans.
Related Terms
- Aristolochia: A large plant genus from which Aristolochic acid is commonly derived.
- Asarum: A plant genus that also contains Aristolochic acid.
- Carcinogen: A substance capable of causing cancer in living tissue.
- Mutagen: An agent, such as radiation or a chemical substance, that causes genetic mutation.
- Nephrotoxin: A toxin that specifically damages the kidneys.
See Also
External links
- Medical encyclopedia article on Aristolochic acid
- Wikipedia's article - Aristolochic acid
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