Bromazolam

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Bromazolam.svg

Bromazolam is a benzodiazepine derivative that has been used in research and has potential applications in the treatment of anxiety and insomnia. It is structurally related to other benzodiazepines such as alprazolam and bromazepam.

Chemical Properties

Bromazolam is a chemical compound with the formula C17H13BrN4. It is characterized by the presence of a bromine atom, which differentiates it from other benzodiazepines. The compound is typically synthesized in a laboratory setting and is not commonly found in nature.

Pharmacology

Bromazolam acts on the central nervous system by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor. This action results in sedative, anxiolytic, muscle relaxant, and anticonvulsant effects. The pharmacokinetics and metabolism of bromazolam are similar to those of other benzodiazepines, involving hepatic metabolism and renal excretion.

Medical Uses

While bromazolam is not widely used in clinical practice, it has potential applications in the treatment of anxiety disorders, panic disorders, and insomnia. Its efficacy and safety profile are subjects of ongoing research.

Side Effects

As with other benzodiazepines, bromazolam can cause a range of side effects, including drowsiness, dizziness, confusion, and impaired coordination. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.

Legal Status

The legal status of bromazolam varies by country. In some jurisdictions, it may be classified as a controlled substance due to its potential for abuse and dependence.

See Also

References



External Links

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Contributors: Prab R. Tumpati, MD