CRSP3
CRSP3
CRSP3 (pronounced "crisp three") is a gene that encodes a protein in humans. It is also known as Mediator complex subunit 27 or MED27.
Pronunciation
CRSP3 is pronounced as "crisp three".
Etymology
The term CRSP3 is an acronym for CoRe Set Protein 3. It is named so because it is one of the proteins in the core set of proteins that are part of the Mediator complex, a key component in the regulation of gene transcription.
Function
The CRSP3 gene provides instructions for making a protein that is part of the Mediator complex. This complex is necessary for the successful transcription of nearly all class II gene promoters in humans. It plays a role in both the activation and repression of transcription.
Related Terms
- Gene: A gene is a unit of heredity which is transferred from a parent to offspring and is held to determine some characteristic of the offspring.
- Protein: Proteins are large, complex molecules that play many critical roles in the body. They do most of the work in cells and are required for the structure, function, and regulation of the body's tissues and organs.
- Transcription (genetics): Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase.
- Mediator complex: The Mediator complex is a multi-protein complex that functions as a transcriptional coactivator in all eukaryotes. It interacts with RNA polymerase II and the general transcription factors to form the preinitiation complex.
External links
- Medical encyclopedia article on CRSP3
- Wikipedia's article - CRSP3
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski