Cetiedil
Cetiedil is a vasodilator and antianginal drug that was developed in the 1970s. It is classified under the pharmacological category of calcium channel blockers, which are drugs that dilate the arteries and reduce pressure within the blood vessels. Cetiedil is not widely used today due to the development of newer and more effective drugs.
History
Cetiedil was first synthesized in the 1970s by the pharmaceutical company Ciba-Geigy. It was developed as a treatment for angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. The drug works by relaxing the muscles of the blood vessels, thereby increasing blood flow and reducing heart strain.
Pharmacology
As a calcium channel blocker, Cetiedil works by inhibiting the movement of calcium ions into the cells of the heart and blood vessels. This action relaxes the blood vessels, allowing blood to flow more easily and reducing the workload of the heart.
Cetiedil is administered orally and is metabolized in the liver. Its effects can last for several hours, making it suitable for the management of chronic conditions such as angina and hypertension.
Side Effects
Like all drugs, Cetiedil can cause side effects. These may include dizziness, headache, nausea, and flushing. In rare cases, it can cause more serious side effects such as arrhythmia or hypotension. Patients are advised to consult their healthcare provider if they experience any adverse effects while taking this medication.
Current Use
Cetiedil is not widely used today due to the development of newer and more effective drugs. However, it may still be prescribed in certain cases where other treatments are not suitable or have not been effective.
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Contributors: Prab R. Tumpati, MD