Cis-vaccenic acid
Cis-vaccenic acid is a monounsaturated fatty acid that is naturally occurring in the lipid structure of various organisms. It is a type of fatty acid that is characterized by the presence of a single double bond in its structure. The term "cis" refers to the geometric configuration of the double bond, where the hydrogen atoms are on the same side of the bond.
Structure and Properties
Cis-vaccenic acid has the chemical formula C18H34O2. It is a long-chain fatty acid with 18 carbon atoms, and the double bond is located at the 11th carbon atom from the methyl end of the chain. The cis configuration of the double bond results in a bend in the molecule, which influences its physical properties and its interactions with other molecules.
Sources and Biosynthesis
Cis-vaccenic acid is found in various natural sources, including animal fat, dairy products, and certain types of plants. It is also produced by certain types of bacteria, including those in the genus Streptococcus and Lactobacillus.
In organisms, cis-vaccenic acid is synthesized from palmitic acid through a series of enzymatic reactions. The enzyme stearoyl-CoA desaturase plays a key role in this process, introducing the double bond into the fatty acid chain.
Biological Role and Health Effects
Cis-vaccenic acid is an important component of cell membranes, contributing to their fluidity and function. It is also involved in various biological processes, including inflammation and immune response.
Several studies have suggested that cis-vaccenic acid may have potential health benefits. For example, it has been associated with reduced risk of cardiovascular disease and improved insulin sensitivity. However, more research is needed to fully understand its role in human health.
See Also
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Contributors: Prab R. Tumpati, MD