Crossover study
Crossover study
A Crossover study (pronounced: /ˈkrɒsˌoʊvər ˈstʌdi/) is a type of clinical trial where participants receive a sequence of different treatments or interventions. The aim is to reduce the influence of confounding variables and increase the reliability of results.
Etymology
The term "crossover" in this context is derived from the concept of participants "crossing over" from one treatment to another during the course of the study.
Description
In a crossover study, each participant acts as their own control group, as they receive both the experimental treatment and the control or placebo. The order in which treatments are received is usually randomized to minimize bias. This type of study design is particularly useful when the effect of the treatment is temporary and does not have lasting effects.
Crossover studies are often used in pharmacology to test the effectiveness of different drugs or drug dosages. They can also be used in other fields such as psychology and nutrition science.
Advantages and Disadvantages
Advantages of crossover studies include a reduction in the number of participants needed and the ability to control for individual differences. However, they may not be suitable for treatments with long-lasting effects or when the condition being studied is unstable. They are also subject to period effects and carryover effects, where the effect of the first treatment carries over into the period of the second treatment.
Related Terms
- Randomized controlled trial
- Placebo-controlled study
- Parallel group study
- Single-blind study
- Double-blind study
External links
- Medical encyclopedia article on Crossover study
- Wikipedia's article - Crossover study
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski