Elesclomol
Elesclomol
Elesclomol (pronounced el-es-klo-mol) is a synthetic, small molecule with potential antineoplastic activity.
Etymology
The term "Elesclomol" is a coined name for this specific compound, and does not have a known etymology.
Definition
Elesclomol selectively induces oxidative stress and apoptosis in cancer cells by increasing the levels of reactive oxygen species (ROS) while leaving normal cells unaffected. This is achieved by disrupting the function of mitochondria, the cell's energy-producing structures, and causing an imbalance in the cell's redox state.
Related Terms
- Antineoplastic: A substance that inhibits or prevents the growth and spread of cancer cells.
- Apoptosis: A form of programmed cell death that occurs in multicellular organisms.
- Mitochondria: An organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur.
- Reactive Oxygen Species (ROS): Chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen.
Usage
Elesclomol is currently being studied in clinical trials for its potential use in the treatment of various types of cancer, including melanoma, ovarian cancer, and breast cancer.
See Also
External links
- Medical encyclopedia article on Elesclomol
- Wikipedia's article - Elesclomol
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