Ezlopitant
Ezlopitant
Ezlopitant (pronunciation: /ɛzˈlɒpɪtænt/) is a neurokinin 1 receptor antagonist used in the treatment of chemotherapy-induced nausea and vomiting (CINV).
Etymology
The term "Ezlopitant" is derived from the chemical name of the drug, which is (2S,3S)-2-phenyl-3-[[(3R)-1-piperidinylmethyl]amino]-2-quinuclidinecarboxylic acid 1-azabicyclo[2.2.2]oct-3-yl ester. The "-pitant" suffix is common among neurokinin 1 receptor antagonists.
Usage
Ezlopitant is used in the prevention and treatment of CINV, a common side effect of chemotherapy. It works by blocking the action of substance P, a neurotransmitter involved in the vomiting reflex.
Related Terms
- Neurokinin 1 receptor: A type of receptor in the body that binds to substance P.
- Chemotherapy-induced nausea and vomiting: A common side effect of chemotherapy treatment.
- Substance P: A neurotransmitter involved in the vomiting reflex.
See Also
- Neurokinin 1 receptor antagonist: A class of drugs that includes Ezlopitant.
- Chemotherapy: The use of drugs to treat diseases such as cancer.
External links
- Medical encyclopedia article on Ezlopitant
- Wikipedia's article - Ezlopitant
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