Fungal pneumonia
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Fungal pneumonia | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Cough, fever, chest pain, shortness of breath |
| Complications | Respiratory failure, sepsis |
| Onset | Gradual |
| Duration | Varies |
| Types | N/A |
| Causes | Fungal infection by species such as Aspergillus, Histoplasma, Coccidioides, Blastomyces |
| Risks | Immunocompromised state, HIV/AIDS, chemotherapy, organ transplant |
| Diagnosis | Chest X-ray, CT scan, sputum culture, bronchoscopy |
| Differential diagnosis | Bacterial pneumonia, viral pneumonia, tuberculosis |
| Prevention | Avoidance of exposure in high-risk areas, prophylactic antifungal medication |
| Treatment | Antifungal medication such as voriconazole, amphotericin B |
| Medication | N/A |
| Prognosis | Variable, depends on underlying health and timeliness of treatment |
| Frequency | Rare in healthy individuals, more common in immunocompromised |
| Deaths | N/A |
An overview of fungal pneumonia, focusing on pulmonary aspergillosis
Fungal pneumonia is an infectious disease of the lungs caused by fungi. It is a type of pneumonia that occurs when fungal spores are inhaled and infect the lung tissue. This condition is more common in individuals with weakened immune systems, such as those with HIV/AIDS, cancer, or those taking immunosuppressive medications.
Causes
Fungal pneumonia can be caused by various types of fungi. The most common fungi that cause pneumonia include:
- Aspergillus species, leading to pulmonary aspergillosis
- Histoplasma capsulatum, causing histoplasmosis
- Coccidioides immitis, responsible for coccidioidomycosis
- Cryptococcus neoformans, leading to cryptococcosis
Symptoms
The symptoms of fungal pneumonia can vary depending on the specific fungus involved but often include:
Diagnosis
Diagnosis of fungal pneumonia typically involves a combination of:
- Chest X-ray or CT scan to identify lung abnormalities
- Sputum culture or bronchoalveolar lavage to identify the fungal organism
- Blood tests to detect fungal antigens or antibodies
Treatment
Treatment of fungal pneumonia depends on the specific fungus causing the infection. Common treatments include:
- Antifungal medications such as amphotericin B, itraconazole, or voriconazole
- Supportive care, including oxygen therapy and mechanical ventilation if necessary
Pulmonary Aspergillosis
Pulmonary aspergillosis is a type of fungal pneumonia caused by the Aspergillus species, most commonly Aspergillus fumigatus. It can manifest in several forms, including:
- Allergic bronchopulmonary aspergillosis (ABPA)
- Chronic pulmonary aspergillosis
- Invasive aspergillosis
Risk Factors
Individuals at higher risk for pulmonary aspergillosis include those with:
- Chronic lung disease
- Immunocompromised status
- Corticosteroid use
Clinical Presentation
Symptoms of pulmonary aspergillosis can include:
- Persistent cough
- Hemoptysis (coughing up blood)
- Worsening asthma symptoms in ABPA
Management
Management of pulmonary aspergillosis involves:
- Antifungal therapy, often with voriconazole or amphotericin B
- Surgical intervention in cases of aspergilloma
- Corticosteroids for ABPA
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Contributors: Prab R. Tumpati, MD