Generalized lentiginosis

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Generalized lentiginosis
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Synonyms	Lentiginosis profusa
Pronounce	N/A
Specialty	N/A
Symptoms	Multiple lentigines
Complications	Cardiac abnormalities, endocrine disorders
Onset	Childhood
Duration	Lifelong
Types	N/A
Causes	Genetic mutation
Risks	Family history
Diagnosis	Clinical examination, genetic testing
Differential diagnosis	Peutz-Jeghers syndrome, LEOPARD syndrome
Prevention	None
Treatment	Laser therapy, cosmetic camouflage
Medication	N/A
Prognosis	Generally good, but depends on associated conditions
Frequency	Rare
Deaths	N/A

Generalized lentiginosis is a rare skin condition characterized by the widespread presence of lentigines, which are small, pigmented spots on the skin. This condition is not associated with any other physical abnormalities or illnesses.

Symptoms

The primary symptom of generalized lentiginosis is the presence of numerous lentigines. These spots are typically small, less than 5mm in diameter, and are darker than the surrounding skin. They can appear anywhere on the body, but are most commonly found on the trunk and extremities. The lentigines in generalized lentiginosis are not associated with an increased risk of skin cancer.

Causes

The cause of generalized lentiginosis is not well understood. It is thought to be a genetic condition, as it often runs in families. However, the specific genes involved have not been identified.

Diagnosis

Generalized lentiginosis is diagnosed based on the appearance of the skin. A dermatologist can usually make the diagnosis based on a physical examination. In some cases, a skin biopsy may be performed to confirm the diagnosis.

Treatment

There is no cure for generalized lentiginosis, and treatment is not usually necessary. If the appearance of the lentigines is bothersome, they can be lightened with skin-bleaching creams or removed with laser therapy.

See also

• Lentigo
• Skin pigmentation
• Dermatology

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