Giant-cell glioblastoma

Giant-cell glioblastoma (pronunciation: jai-ant sel gli-o-blas-to-ma) is a rare and aggressive subtype of glioblastoma, a type of brain tumor.

Etymology

The term "giant-cell glioblastoma" is derived from the presence of unusually large, multinucleated cells (giant cells) found in these tumors. The term "glioblastoma" originates from the Greek words "glia," meaning glue, and "blastoma," meaning growth, referring to the tumor's origin in the supportive tissue of the brain.

Definition

Giant-cell glioblastoma is characterized by the presence of giant cells with multiple nuclei. These tumors are highly malignant and grow rapidly, often leading to severe neurological symptoms. Despite their aggressive nature, giant-cell glioblastomas are slightly more responsive to therapy than other types of glioblastomas.

Symptoms

Symptoms of giant-cell glioblastoma can vary depending on the tumor's location and size. Common symptoms include headaches, seizures, and neurological deficits such as weakness or numbness on one side of the body.

Diagnosis

Diagnosis of giant-cell glioblastoma typically involves a combination of neurological examination, imaging studies such as MRI or CT scan, and biopsy to confirm the presence of giant cells.

Treatment

Treatment for giant-cell glioblastoma usually involves a combination of surgery, radiation therapy, and chemotherapy. Despite aggressive treatment, the prognosis for patients with giant-cell glioblastoma is generally poor due to the tumor's rapid growth and resistance to therapy.

Related Terms

External links

Medical encyclopedia article on Giant-cell glioblastoma
Wikipedia's article - Giant-cell glioblastoma

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Giant-cell glioblastoma